Skip to content
Primary Menu

Home Burrows Laboratory

Burrows Laboratory


Cynthia J. Burrows

We are a group of nucleic acid chemists with a focus on chemical modifications to DNA and RNA bases. In DNA, such modifications are typically thought to be deleterious leading to mutations and thus to genetic diseases and cancer; however, we recently showed that oxidized guanosine can function epigenetically to upregulate genes in response to oxidative stress.  Modified bases in RNA are considered epitranscriptomic—they help punctuate and regulate the transcriptome.  We use methods in chemical biology (synthesis, enzymology, biophysical methods) to sequence DNA and RNA for modifications and to understand structure (e.g. G-quadruplexes) and cell biology assays to understand the function of base modifications in cells.  Members of the lab include organic, biological, analytical and biophysical chemists.

Cynthia J. Burrows Bio

Dr. Cynthia J. Burrows is Distinguished Professor of Chemistry at the University of Utah. She was raised in St. Paul, Minnesota, and Boulder, Colorado. Her undergraduate training was in physical organic chemistry with Prof. Stan Cristol at the University of Colorado, and her Ph.D. work was with Prof. Barry Carpenter at Cornell University, followed by an NSF-CNRS postdoctoral fellowship in the laboratory of Nobel Laureate Prof. Jean-Marie Lehn, Université Louis Pasteur, Strasbourg.  She began her independent career as an assistant professor of chemistry at the State University of New York at Stony Brook and was promoted to full professor in 1992 before returning to the West to take a position in Salt Lake City in 1995.

Prof. Burrows has been a member of numerous editorial boards and review panels; from 2001-2013, she served as Senior Editor of the Journal of Organic Chemistry, and in 2014, she began as Editor-in-Chief of Accounts of Chemical Research. She is a past recipient of the Robert Parry Teaching Award and, in 2011, of the University Distinguished Teaching Award; her research was recently recognized with the ACS Utah Award, ACS Cope Scholar Award, and the University of Utah's Distinguished Creative and Scholarly Research Award.  In 2009, she was inducted into the American Academy of Arts and Sciences, and in 2013 she was appointed the inaugural holder of the Thatcher Presidential Endowed Chair of Biological Chemistry.  In 2014, she received the Linda K. Amos Award for Distinguished Service to Women at the University of Utah and was elected to the National Academy of Sciences.  In 2019, she received the highest award of the University of Utah, the Rosenblatt Prize for Excellence.

Cynthia J. Burrows
Distinguished Professor
Thatcher Presidential Endowed Chair of Biological Chemistry
burrows@chem.utah.edu