Coupling phenols and allylic alcohols
Palladium-catalyzed enantioselective oxa-Heck reaction creates chemical building blocks that are difficult to make through standard synthetic procedures By Bethany Halford Reprinted from C&EN Although chemists have plenty of ways to add carbon atoms to alkenes—including the Nobel Prize-winning Heck reaction—they have fewer options when working with heteroatom nucleophiles, such as alcohols. Now, Matthew S. Sigman […]
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